Last meeting:
Jake Delhomme passed for 191 yards and a touchdown to lead the Panthers past the Bills, 13-9, in Week 12 of 2005.

Streaks:
The Bills have won three of the four all-time meetings.

Last week:
Buffalo had six interceptions in a 16-13 overtime victoryagainst the Jets. ... The Panthers earned their second straight win, beating the Buccaneers 28-21.

Keep your eye on ...

Steve Smith's role in Carolina's offense: Usually after wins, a locker room is jubilant and players are in a celebratory mood. That was not the case with Smith last week. The star receiver told The Charlotte Observer, "I'm no longer an asset to this team," after catching just one pass for 4 yards in the victory over Tampa Bay. The Panthers will need a motivated Smith to make a run this season. Look for him to get involved early against the Bills.

Julius Peppers' sudden surge: In his first three games, Peppers had just nine tackles and one sack. Over the past two weeks, however, Peppers has woken up. He has 12 tackles and four sacks in his last two outings and now gets to face a struggling Bills offensive line that has surrendered 19 sacks already this season.

Paul Posluszny's leadership: The second-year Bills linebacker is a rock on the defense. He missed the final 13 games of his rookie season in 2007 with a broken forearm and was out for four weeks with a less severe broken forearm this season. He returned last Sunday and his interception helped set up Buffalo's winning field goal. He is an inspirational force on the defense and his presence provides the team a boost.

Did you know?

Bills WR Lee Evans has a catch in 79 of his past 80 games. ... Buffalo K Rian Lindell connected on his 11th game-winning field goal last week. ... Carolina QB Jake Delhomme has won eight of his last 10 games against the AFC. ... When Jonathan Stewart has at least 14 carries, the Panthers are 9-0.

Well I don't know a whole lot going into this one. Hopefully our line is getting better and Meredith is making a difference out there. Byrd was impressive in coverage, not so much in run defense. I wouldn't mind having him and Whitner out there together.

Don't know who's lining up behind center either. Hopefully Trent is healthy. I guess we have decent chances in this one. I'm just gonna hope we win, the Jets keep reeling, the Saints smack the Dolphins, and the Pats lose to Tampa (lmao) ok 2 out of 3 will work for me

The Panthers have had trouble with good teams. We had issues with the D-line and hope they are now fixed with the recent additions. Smith has been a non-factor due to Jakes throwing to the other team. Our running game seems to be on track , so our passing game could do better if you pay attention to the run.

I hope that we both see some upswing in our repesctive teams. Injuries and lack of direction threaten both our teams..and by that I mean one man goes out and we are in a hurt locker, since we are bringing in trades like crazy. You have a good QB, we have a QB, but our only solice is that he's not fumbled any handoffs lately, and with two RB's like we have..that might get us through the day.

Our two unknowns, of course, are TO and Smith. THAT might be the surprise of the game for either/both of us! Let's both stay healthy..there is plenty of tough football ahead for both of us.

You know what they say. A win is a win. Jake Delhomme is terrible......and Jairus Byrd is a beast. Our defense really kept the offense in this one for the longest since the offense couldn't do much of anything for most of this one. I kind of feel for Carolina because they are probably a much better team with a decent QB

Congrats - nice going.

First yeah Bryd a straight ball hawk like his pops is in super tecmo bowl for the NES..lol. Fred jackson has no right to be a return man. He looked plain silly just standing there after fielding punts. Waiting to be surrounded by carolina. I want Roscoe back there ASAP! Also just put Terrance back as the KR he had a nice run back on his KO return. Maybe April was having someone to show Jackson how its done....Also i liked Fitzpatrick and his willingness to involve his receivers in the game. Taking some shots downfield...Not like Mr. Checkdown does