NFL Odds Week 10 - Week Ten NFL Football Odds NFL Game Odds 11/8 - 11/12, 2012
| date & time | favorite | spread | underdog | total | money odds |
| 11/8 8:25 et | indianapolis | -3 | at jacksonville | 42 | -$175 +$155 |
| 11/11 1:00 et | at new england | -11 | buffalo | 51 | -$700 +$500 |
| 11/11 1:00 et | ny giants | -4 | at cincinnati | 48.5 | -$215 +$185 |
| 11/11 1:00 et | at tampa bay | -3 | san diego | 47.5 | -$170 +$150 |
| 11/11 1:00 et | denver | -4 | at carolina | 47 | -$205 +$175 |
| 11/11 1:00 et | at miami | -6 | tennessee | 44 | -$270 +$230 |
| 11/11 1:00 et | at baltimore | -7.5 | oakland | 46 | -$360 +$300 |
| 11/11 1:00 et | atlanta | -2.5 | at new orleans | 53.5 | -$140 +$120 |
| 11/11 1:00 et | detroit | -2 | at minnesota | 47 | -$135 +$115 |
| 11/11 4:05 et | at seattle | -6 | ny jets | 38.5 | -$280 +$240 |
| 11/11 4:25 et | dallas | -1.5 | at philadelphia | 44.5 | -$125 +$105 |
| 11/11 4:25 et | at san francisco | -11.5 | st. louis | 38.5 | -$700 +$500 |
| 11/11 8:30 et | at chicago | -1 | houston | 41.5 | -$120 +$100 |
Monday Night Football Odds
| 11/12 8:40 ET | At Pittsburgh | -12 | Kansas City | 42.5 | -$825 +$600 |
Bye Week: Arizona, Cleveland, Green Bay, Washington